NRMA-8
Product Specifications
UNSPSC Description
NRMA-8 is a brain-penetrant small molecule nuclear receptor modulator. NRMA-8 is promising for research of central nervous system disorders, including Alzheimer's disease, Parkinson's disease, demylenation disorders and glioblastomas[1][2].
Target Antigen
FAAH
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease;Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nrma-8.html
Smiles
O=C(C1=CC=C(C=C1)Cl)NCCC2=CC=C(C=C2)OC(C)(C)C(NC)=O
Molecular Weight
374.86
References & Citations
[1]SCANLAN Thomas S, et al. N-methyl amide prodrugs of small molecule nuclear receptor modulators. WO2019168842. 2018 March 02.|[2]Ferrara SJ, et al. A CNS-Targeting Prodrug Strategy for Nuclear Receptor Modulators. J Med Chem. 2020 Sep 10;63(17):9742-9751.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-164506/NRMA-8-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-164506/
Clinical Information
No Development Reported
CAS Number
2375659-15-5
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
