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Epiallopregnanolone

Product Specifications

UNSPSC Description

Epiallopregnanolone (5α,3β-THDOC), a 3β-hydroxy neurosteroid, an antagonist at GABAA receptors and a NMDA receptor enhancer[1].

Target Antigen

GABA Receptor; iGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel;Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/epiallopregnanolone.html

Solubility

10 mM in DMSO

Smiles

C[C@]12[C@]([H])([C@@]3(CC[C@]4(C[C@H](CC[C@@]4([C@]3(CC2)[H])C)O)[H])[H])CC[C@@H]1C(CO)=O

Molecular Weight

334.49

References & Citations

[1]Brett C Ginsburg, et al. Alphaxalone and epiallopregnanolone in rats trained to discriminate ethanol. Alcohol Clin Exp Res. 2005 Sep;29(9):1621-9.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-124463/Epiallopregnanolone-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-124463/

Clinical Information

No Development Reported

CAS Number

567-01-1

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