Nitroxoline-d4
Product Specifications
UNSPSC Description
Nitroxoline-d4 is the deuterium labeled Nitroxoline. Nitroxoline is an antibiotic that has proven to be very effective at combating biofilm infections. Nitroxoline functions by chelating Fe2+ and Zn2+ ions from the biofilm matrix[1][2].
Target Antigen
Antibiotic; Autophagy; Bacterial
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection;Autophagy
Field of Research
Infection; Cancer
Solubility
10 mM in DMSO
Smiles
OC1=C2N=C([2H])C([2H])=C([2H])C2=C([N+]([O-])=O)C=C1[2H]
Molecular Weight
194.18
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Abouelhassan Y, et al. Nitroxoline: a broad-spectrum biofilm-eradicating agent against pathogenic bacteria. Int J Antimicrob Agents. 2017 Feb;49(2):247-251.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
Curated Selection
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