Dapoxetine

Dapoxetine (LY-210448) is an orally active and selective serotonin reuptake inhibitor (SSRI) . Dapoxetine can be used for the research of premature ejaculation (PE) [1].

Product Specifications

CAS Number

[119356-77-3]

Product Name Alternative

(S) - (+) -Dapoxetine; LY-210448

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Serotonin Transporter

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/dapoxetine.html

Solubility

10 mM in DMSO

Smiles

CN(C)[C@H](C1=CC=CC=C1)CCOC2=CC=CC3=C2C=CC=C3

Molecular Formula

C21H23NO

Molecular Weight

305.41

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Muammer Kendirci, et al. Dapoxetine, a novel selective serotonin transport inhibitor for the treatment of premature ejaculation. Ther Clin Risk Manag. 2007 Jun;3 (2) :277-89.|[2]Rabab H Sayed, et al. Dapoxetine attenuates testosterone-induced prostatic hyperplasia in rats by the regulation of inflammatory and apoptotic proteins. Toxicol Appl Pharmacol. 2016 Nov 15;311:52-60.