Mosapride-d5
Product Specifications
UNSPSC Description
Mosapride-d5 is the deuterium labeled Mosapride. Mosapride is a gastroprokinetic agent that acts as a selective 5HT4 agonist.
Target Antigen
5-HT Receptor; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein;Neuronal Signaling;Others
Field of Research
Neurological Disease
Solubility
10 mM in DMSO
Smiles
FC(C=C1)=CC=C1CN(CCO2)CC2CNC(C3=C(C=C(C(Cl)=C3)N)OC([2H])([2H])C([2H])([2H])[2H])=O
Molecular Weight
426.92
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Tack J, et al. Systematic review: cardiovascular safety profile of 5-HT(4) agonists developed for gastrointestinal disorders. Aliment Pharmacol Ther. 2012 Apr;35(7):745-67.|[3]Curran MP, et al. Mosapride in gastrointestinal disorders. Drugs. 2008;68(7):981-91.|[4]Odaka T, et al. Serotonin 5- HT4 receptor agonist (mosapride citrate). Nihon Rinsho. 2006 Aug;64(8):1491-4.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
CAS Number
1246820-66-5
Curated Selection
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