Niacin-13C6

Niacin-13C6 is the 13C-labeled Niacin. Niacin (Nicotinic acid) is a vitamin and is part of the vitamin B group.

Product Specifications

CAS Number

[1189954-79-7]

Product Name Alternative

Nicotinic acid-13C6; Vitamin B3-13C6

UNSPSC

12352005

Hazard Statement

H319

Target

Autophagy; Endogenous Metabolite

Type

Isotope-Labeled Compounds

Related Pathways

Autophagy; Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/niacin-13c6.html

Purity

99.90

Solubility

DMSO : 50mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 10mg/mL (ultrasonic)

Smiles

O=[13C]([13C]1=[13CH][13CH]=[13CH]N=[13CH]1)O

Molecular Formula

13C6H5NO2

Molecular Weight

129.07

Precautions

H319

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Bruckert E, et al. Meta-analysis of the effect of nicotinic acid alone or in combination on cardiovascular events and atherosclerosis. Atherosclerosis. 2010 Jun;210 (2) :353-61.|[3]Wan P, et al. Pellagra: a review with emphasis on photosensitivity. Br J Dermatol. 2011 Jun;164 (6) :1188-200.|[4]Ishii N, et al. Pellagra among chronic alcoholics: clinical and pathological study of 20 necropsy cases. J Neurol Neurosurg Psychiatry. 1981 Mar;44 (3) :209-15.