Prilocaine (acetate)
Prilocaine acetate, an amino amide, is a Na/K-ATPase inhibitor. Prilocaine acetate has neurotoxic effects[1][2].
Product Specifications
UNSPSC
12352005
Target
Na+/K+ ATPase
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/prilocaine-acetate.html
Solubility
10 mM in DMSO
Smiles
CC(NCCC)C(NC1=CC=CC=C1C)=O.CC(O)=O
Molecular Formula
C15H24N2O3
Molecular Weight
280.36
References & Citations
[1]M Mete, et al. Neurotoxic effects of local anesthetics on the mouse neuroblastoma NB2a cell line. Biotech Histochem. 2015 Apr;90 (3) :216-22. |[2]H Kutchai, et al. Effects of local anaesthetics on the activity of the Na, K-ATPase of canine renal medulla. Pharmacol Res. 2000 Jan;41 (1) :1-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 4
Curated Selection
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