Prilocaine (acetate)

Prilocaine acetate, an amino amide, is a Na/K-ATPase inhibitor. Prilocaine acetate has neurotoxic effects[1][2].

Product Specifications

UNSPSC

12352005

Target

Na+/K+ ATPase

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/prilocaine-acetate.html

Solubility

10 mM in DMSO

Smiles

CC(NCCC)C(NC1=CC=CC=C1C)=O.CC(O)=O

Molecular Formula

C15H24N2O3

Molecular Weight

280.36

References & Citations

[1]M Mete, et al. Neurotoxic effects of local anesthetics on the mouse neuroblastoma NB2a cell line. Biotech Histochem. 2015 Apr;90 (3) :216-22. |[2]H Kutchai, et al. Effects of local anaesthetics on the activity of the Na, K-ATPase of canine renal medulla. Pharmacol Res. 2000 Jan;41 (1) :1-7.