Prilocaine-d7 (hydrochloride)
Product Specifications
UNSPSC Description
Prilocaine-d7 (hydrochloride) is deuterium labeled Prilocaine (hydrochloride). Prilocaine hydrochloride, an amino amide, is a Na, K-ATPase inhibitor. Prilocaine has neurotoxic effects[1][2].
Target Antigen
Isotope-Labeled Compounds; Na+/K+ ATPase
Type
Isotope-Labeled Compounds
Related Pathways
Membrane Transporter/Ion Channel;Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Purity
98.16
Solubility
10 mM in DMSO
Smiles
CC(NCCC)C(NC1=C(C([2H])([2H])[2H])C([2H])=C([2H])C([2H])=C1[2H])=O.Cl
Molecular Weight
263.81
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.|[2]H Kutchai, et al. Effects of local anaesthetics on the activity of the Na,K-ATPase of canine renal medulla. Pharmacol Res. 2000 Jan;41(1):1-7.|[3]M Mete, et al. Neurotoxic effects of local anesthetics on the mouse neuroblastoma NB2a cell line. Biotech Histochem. 2015 Apr;90(3):216-22.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Clinical Information
No Development Reported
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