Indalpine

Indalpine (LM 5008) is a potent and selective 5-HT uptake blocker. Indalpine is potent in displacing 3H-5-HT bound to brain membranes with the IC50 of 36 μM[1]. Indalpine, two antidepressant agent[2].

Product Specifications

CAS Number

[63758-79-2]

Product Name Alternative

LM 5008

UNSPSC

12352005

Hazard Statement

H315-H319-H320

Target

Serotonin Transporter

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/indalpine.html

Solubility

10 mM in DMSO

Smiles

C1(CCC2CCNCC2)=CNC3=C1C=CC=C3

Molecular Formula

C15H20N2

Molecular Weight

228.33

Precautions

P264-P280-P302+P352-P305+P351+P338-P362

References & Citations

[1]R Samanin, et al. Further studies on the mechanism of serotonin-dependent anorexia in rats. Psychopharmacology (Berl) . 1980;68 (1) :99-104.|[2]P Blier, et al. Effects of the two antidepressant drugs mianserin and Indalpine on the serotonergic system: single-cell studies in the rat. Psychopharmacology (Berl) . 1984;84 (2) :242-9.