Viomycin

Viomycin is a potent antibiotic against Mycobacteria. Viomycin rapidly inhibits polypeptide chain elongation when added to purified endogenous Escherichia coli polysomes actively engaged in polypeptide synthesis[1][2].

Product Specifications

CAS Number

[32988-50-4]

UNSPSC

12352005

Hazard Statement

H315-H319-H320

Target

Antibiotic; Bacterial

Type

Natural Products

Related Pathways

Anti-infection

Applications

Cancer-programmed cell death

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/viomycin.html

Solubility

10 mM in DMSO

Smiles

O=C(NC[C@@H](C(N[C@H]1CO)=O)NC(C[C@@H](N)CCCN)=O)[C@](NC(/C(NC([C@@H](NC1=O)CO)=O)=C/NC(N)=O)=O)([H])[C@@](NC(N)=N2)([H])C[C@@H]2O

Molecular Formula

C25H43N13O10

Molecular Weight

685.69

Precautions

P264-P280-P302+P352-P305+P351+P338-P362

References & Citations

[1]FINLAY AC, et al. Viomycin a new antibiotic active against Mycobacteria. Am Rev Tuberc. 1951 Jan;63 (1) :1-3.|[2]Modolell J, Vázquez. The inhibition of ribosomal translocation by viomycin. Eur J Biochem. 1977 Dec;81 (3) :491-7.