Azilsartan methyl ester

Azilsartan methyl ester, a derivative of Azilsartan (HY-14914), is an angiotensin II receptor antagonist that plays an important role in hypertension[1].

Product Specifications

CAS Number

[147403-52-9]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Angiotensin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/azilsartan-methyl-ester.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=C(C2=CC=C1)N(C(OCC)=N2)CC3=CC=C(C4=C(C(N5)=NOC5=O)C=CC=C4)C=C3)OC

Molecular Formula

C26H22N4O5

Molecular Weight

470.48

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Alison Handley, et al. Safety and tolerability of azilsartan medoxomil in subjects with essential hypertension: a one-year, phase 3, open-label study. Clin Exp Hypertens. 2016;38 (2) :180-8.