Ispinesib-d5
Ispinesib-d5 (SB-715992-d5) is a deuterium labeled Ispinesib (HY-50759) . Ispinesib is a specific inhibitor of kinesin spindle protein (KSP) [1].
Product Specifications
Product Name Alternative
SB-715992-d5
UNSPSC
12352005
Target
Apoptosis; Kinesin
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Solubility
10 mM in DMSO
Smiles
O=C1N(CC2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])C([C@@H](C(C)C)N(CCCN)C(C3=CC=C(C)C=C3)=O)=NC4=CC(Cl)=CC=C14
Molecular Formula
C30H28D5ClN4O2
Molecular Weight
522.09
References & Citations
[1]Purcell JW, et al. Activity of the kinesin spindle protein inhibitor ispinesib (SB-715992) in models of breast cancer. Clin Cancer Res. 2010 Jan 15;16 (2) :566-76.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Curated Selection
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