Monomethyl auristatin E intermediate-2
Monomethyl auristatin E intermediate-2 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162) . Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[3026596-62-0]
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
Microtubule/Tubulin
Type
ADC Related
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/monomethyl-auristatin-e-intermediate-2.html
Purity
97.54
Solubility
10 mM in DMSO
Smiles
OC([C@H](C)[C@@H](OCOC)[C@H]1N(C(OC(C)(C)C)=O)CCC1)=O
Molecular Formula
C15H27NO6
Molecular Weight
317.38
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Mouse centrosome-associated protein 350 (CEP350) ELISA Kit
Mouse centrosome-associated protein 350 (CEP350) ELISA Kit