Bremelanotide

Bremelanotide (PT-141) is an analogue of α-melanocyte-stimulating hormone (α-MSH) . Bremelanotide activates the mPOA and other hypothalamic and limbic regions of the brain involved in sexual behavior. Bremelanotide can be used for researching hypoactive sexual desire disorders[1].

Product Specifications

CAS Number

[189691-06-3]

Product Name Alternative

PT-141

UNSPSC

12352209

Hazard Statement

H302, H312, H332

Target

Melanocortin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/bremelanotide.html

Purity

99.69

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

O=C(N[C@](CCCCNC(C[C@@H]1NC([C@@H](NC(C)=O)CCCC)=O)=O)([H])C(O)=O)[C@@H](NC([C@@H](NC([C@@](NC([C@@H](NC1=O)CC2=CN=CN2)=O)([H])CC3=CC=CC=C3)=O)CCCNC(N)=N)=O)CC4=CNC5=CC=CC=C45

Molecular Formula

C50H68N14O10

Molecular Weight

1025.16

Precautions

H302, H312, H332

References & Citations

[1]Pfaus J, et al. Bremelanotide: an overview of preclinical CNS effects on female sexual function. J Sex Med. 2007 Nov;4 Suppl 4:269-79.|[2]Molinoff PB, et al. PT-141: a melanocortin agonist for the treatment of sexual dysfunction. Ann N Y Acad Sci. 2003 Jun;994:96-102.