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NIBR-17

Product Specifications

UNSPSC Description

NIBR-17 is a pan-class I PI3K inhibitor with suitable pharmacokinetic properties and inhibits tumor growth[1].

Target Antigen

PI3K

Type

Reference compound

Related Pathways

PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/nibr-17.html

Solubility

10 mM in DMSO

Smiles

NC1=NC=C(C2=NC(N3CCOCC3)=NC(NC4=CC=C(OC)N=C4)=C2)C=N1

Molecular Weight

380.40

References & Citations

[1]Burger MT, et al. Synthesis and in Vitro and in Vivo Evaluation of Phosphoinositide-3-kinase Inhibitors. ACS Med Chem Lett. 2010 Oct 13;2(1):34-8.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-18310/NIBR-17-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-18310/

Clinical Information

No Development Reported

CAS Number

944396-88-7

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