Tranylcypromine-d5 (hydrochloride)
Product Specifications
UNSPSC Description
Tranylcypromine-d5 (hydrochloride) is a deuterium labeled (rel)-Tranylcypromine hydrochloride. Tranylcypromine hydrochloride is an irreversible, nonselective monoamine oxidase (MAO) inhibitor used in the treatment of depression. Tranylcypromine hydrochloride is also a lysine-specific demethylase 1 (LSD1) inhibitor, suppresses lesion growth and improves generalized hyperalgesia in mouse with induced endometriosis[1][2].
Target Antigen
Histone Demethylase; Monoamine Oxidase
Type
Isotope-Labeled Compounds
Related Pathways
Epigenetics;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Solubility
10 mM in DMSO
Smiles
N[C@H]1[C@H](C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])C1.[H]Cl
Molecular Weight
174.68
References & Citations
[1]Caraci F, et al. Neuroprotective effects of the monoamine oxidase inhibitor tranylcypromine and its amide derivatives against Aβ(1-42)-induced toxicity. Eur J Pharmacol. 2015 Oct 5;764:256-263.|[2]Sun Q, et al. Tranylcypromine, a lysine-specific demethylase 1 (LSD1) inhibitor, suppresses lesion growth and improves generalized hyperalgesia in mouse with induced endometriosis. Reprod Biol Endocrinol. 2016 Apr 9;14:17.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
CAS Number
107077-98-5
Curated Selection
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