Moiramide B
Moiramide B is a potent acetyl-CoA carboxylase (ACC) inhibitor with an IC50 value of 6 nM. Moiramide B has antibacterial activity[1].
Product Specifications
CAS Number
[155233-31-1]
UNSPSC
12352005
Target
Acetyl-CoA Carboxylase; Bacterial
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/moiramide-b.html
Purity
99.24
Solubility
DMSO : 11.5 mg/mL (ultrasonic; warming)
Smiles
O=C(N1)[C@@H](C([C@H](C(C)C)NC(C[C@H](NC(/C=C/C=C/C)=O)C2=CC=CC=C2)=O)=O)[C@H](C)C1=O
Molecular Formula
C25H31N3O5
Molecular Weight
453.53
References & Citations
[1]Cifone MT, et, al. Heterobivalent Inhibitors of Acetyl-CoA Carboxylase: Drug Target Residence Time and Time-Dependent Antibacterial Activity. J Med Chem. 2022 Dec 22;65 (24) :16510-16525.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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