TME-HYM (PH Probe)
TME-HYM (PH Probe) is a novel fluorescent probe based on acidic tumor microenvironment (TME) activation and organic anion transporting polypeptide (OATPs, overexpressed on cancer cells), and can be selective uptaken. TME-HYM (PH Probe) can selectively lit up cancer cells and tumor tissues, offering dual tumor selectivity for precise visualization of tumor mass[1].
Product Specifications
UNSPSC
12171500
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tme-hym-ph-probe.html
Solubility
10 mM in DMSO
Smiles
CC1=NC(/C=C/C2=[N+](C3=C(C2(C)C)C4=C(C=C(C=C4)I)C=C3)C)=CC5=C1N(C6=CC=CC=C65)CCN7CCOCC7.[I-]
Molecular Formula
C35H36I2N4O
Molecular Weight
782.50
References & Citations
[1]Xu Z, et al. Dual Tumor-Selective β-Carboline-Based Fluorescent Probe for High-Contrast/Rapid Diagnosis of Clinical Tumor Tissues. Mol Pharm. 2024 Jan 1;21 (1) :152-163.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Curated Selection
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