Anticancer agent 174

Anticancer agent 174 (BA-3) is an anticancer agent. Anticancer agent 174 induces tumor cell apoptosis through the mitochondrial pathway. Anticancer agent 174 inhibits cancer cell proliferation in melanoma mouse xenograft model[1].

Product Specifications

CAS Number

[2987820-29-9]

UNSPSC

12352005

Target

Apoptosis

Type

Reference compound

Related Pathways

Apoptosis

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/anticancer-agent-174.html

Solubility

10 mM in DMSO

Smiles

O=C([C@]12[C@@]([C@@H](CC2)C(C)=C)([H])[C@]3([H])[C@@](CC1)([C@]4([C@]([C@@]5([C@@](C(C)([C@H](CC5)O)C)([H])CC4)C)([H])CC3)C)C)OCCCC[N+]6=CC=C(C7=CC=C(C8=CC=C(C=C8)N(C9=CC=CC=C9)C%10=CC=CC=C%10)C%11=NSN=C7%11)C=C6.[Br-]

Molecular Formula

C63H75BrN4O3S

Molecular Weight

1048.26

References & Citations

[1]Wang X, et al. Mitochondria-targeted pentacyclic triterpene NIR-AIE derivatives for enhanced chemotherapeutic and chemo-photodynamic combined therapy. Eur J Med Chem. 2023 Nov 24;264:115975.