V023-9340
V023-9340 is a potent FXR inhibitor with IC50 of 4.27 μM that can be used in NASH (nonalcoholic steatohepatitis) research[1].
Product Specifications
CAS Number
[1048304-96-6]
UNSPSC
12352005
Target
FXR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/v023-9340.html
Solubility
10 mM in DMSO
Smiles
O=C(NCC1=CC=C2OCOC2=C1)CC3=CC=C(C=C3)N(C(C4CCCC4)=O)CC5=CC=CC(C)=C5
Molecular Formula
C30H32N2O4
Molecular Weight
484.59
References & Citations
[1]Cong Chen, et al. Discovery of 4-aminophenylacetamide derivatives as intestine-specific farnesoid X receptor antagonists for the potential treatment of nonalcoholic steatohepatitis. Eur J Med Chem. 2023 Nov 27:264:115992.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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