Hexafluorenium (dibromide)

Hexafluorenium dibromide (Mylaxen) is a potent cholinesterase (ChE) inhibitor with pI50 value of 6.96 and Ki value of 2.4 nM for human plasma cholinesterase (ChE) [1].

Product Specifications

CAS Number

[317-52-2]

Product Name Alternative

Mylaxen

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Cholinesterase (ChE)

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/hexafluorenium-dibromide.html

Solubility

10 mM in DMSO

Smiles

C[N+](C)(C1C2=C(C3=C1C=CC=C3)C=CC=C2)CCCCCC[N+](C)(C4C5=C(C6=C4C=CC=C6)C=CC=C5)C.[Br-].[Br-]

Molecular Formula

C36H42Br2N2

Molecular Weight

662.54

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Schuh FR. Interaction of hexafluorenium with human plasma cholinesterase in comparison with hexamethonium. Naunyn Schmiedebergs Arch Pharmacol. 1976;293 (1) :11-3.