Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Aromatase-IN-3

Aromatase-IN-3 (compound 7d) is an aromatase inhibitor with an IC50 of 54 nM. Through suppressing the conversion of androstenedione to oestrogen caused by aromatase, Aromatase-IN-3 exerts an appreciable tumor growth inhibitory activities against breast cancer cell lines, suggesting its usage for ER+ cancer research[1].

Product Specifications

UNSPSC

12352005

Target

Cytochrome P450

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Cancer; Endocrinology

Assay Protocol

https://www.medchemexpress.com/aromatase-in-3.html

Solubility

10 mM in DMSO

Smiles

O=C(C(OCC)=O)C1=CN(CCCCCNC2=CC=C(/C(C3=CC=CC=C3)=C(C4=CC=CC=C4)\C)C=C2)C5=C1C=CC=C5

Molecular Formula

C38H38N2O3

Molecular Weight

570.72

References & Citations

[1]Rani S, et al. Targeting aromatase to restrain oestrogen production and developing efficacious interventions against ER-positive cancer. Eur J Med Chem. 2023 Dec 31;265:116111.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Aromatase/CYP19A1

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Apg12 (Autophagy-related 12, 4931423H11Rik, A330058M13Rik, Atg12, Apg12L, APG12-like, Atg12L, Autophagy-related protein 12) (MaxLight 550)
A2298-75A1-ML550 100 µL

Apg12 (Autophagy-related 12, 4931423H11Rik, A330058M13Rik, Atg12, Apg12L, APG12-like, Atg12L, Autophagy-related protein 12) (MaxLight 550)

Ask
View Details
PLV3-U6-WTAP-shRNA6-CopGFP-Puro Plasmid
PVT80761 2 µg

PLV3-U6-WTAP-shRNA6-CopGFP-Puro Plasmid

Ask
View Details
Cy3-Linked Polyclonal Antibody to Interleukin 1 Epsilon (IL1e)
MBS2075638-01 0.1 mL

Cy3-Linked Polyclonal Antibody to Interleukin 1 Epsilon (IL1e)

Ask
View Details
Cy3-Linked Polyclonal Antibody to Interleukin 1 Epsilon (IL1e)
MBS2075638-02 0.2 mL

Cy3-Linked Polyclonal Antibody to Interleukin 1 Epsilon (IL1e)

Ask
View Details
Cy3-Linked Polyclonal Antibody to Interleukin 1 Epsilon (IL1e)
MBS2075638-03 0.5 mL

Cy3-Linked Polyclonal Antibody to Interleukin 1 Epsilon (IL1e)

Ask
View Details
Cy3-Linked Polyclonal Antibody to Interleukin 1 Epsilon (IL1e)
MBS2075638-04 1 mL

Cy3-Linked Polyclonal Antibody to Interleukin 1 Epsilon (IL1e)

Ask
View Details