IMP-1575
Product Specifications
UNSPSC Description
IMP-1575 is the most potent Hedgehog acyltransferase (HHAT) inhibitor, with an IC50 of 0.75 μM for inhibition of purified HHAT. IMP-1575 can be used for the research of cancer[1].
Target Antigen
Hedgehog
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/imp-1575.html
Solubility
10 mM in DMSO
Smiles
O=C(N1CCC2=C([C@@H]1C3=NC(C)=CC=C3)C=CS2)CNCC(C)C
Molecular Weight
343.49
References & Citations
[1]Ritzefeld M, et al.Design, Synthesis, and Evaluation of Inhibitors of Hedgehog Acyltransferase. J Med Chem. 1970,2:1061-1078.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-161175/IMP-1575-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-161175/
Clinical Information
No Development Reported
CAS Number
3026255-85-3
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