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Antibacterial agent 175

Product Specifications

UNSPSC Description

Antibacterial agent 175 (compound Y40), a ML346 (HY-18669) analog, is a Sortase A (SrtA) inhibitor. Antibacterial agent 175 shows inhibitory activity on Staphylococcus aureus SrtA and shows inhibitory effects on biofilm formation. Antibacterial agent 175 is an antivirulence agent against S. aureus infections[1].

Target Antigen

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antibacterial-agent-175.html

Solubility

10 mM in DMSO

Smiles

O=C(/C1=C\C=C\C2=CC=C(C=C2)OCC3=CC=C(C=C3)F)NC(NC1=O)=O

Molecular Weight

366.34

References & Citations

[1]Chuan Yue, et al. Structure-Guided Design, Synthesis, and Antivirulence Assessment of Covalent Staphylococcus aureus Sortase A Inhibitors. J Med Chem. 2024 Jan 3.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-161124/Antibacterial-agent-175-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-161124/

Clinical Information

No Development Reported

CAS Number

9007-83-4

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