PROTAC BRD4 Degrader-23
PROTAC BRD4 Degrader-23 (compound 17) is an effective visible-light-controlled degrader. PROTAC BRD4 Degrader-23 can inhibit tumor cell proliferation under 405 nm light irradiation[1].
Product Specifications
UNSPSC
12352005
Target
PROTACs
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-brd4-degrader-23.html
Solubility
10 mM in DMSO
Smiles
O=C(NCCOCCOCCOCC(N[C@@H](C(C)(C)C)CN1[C@H](C(N(CC2=CC=C(C3=C(C)N=CS3)C=C2)CC4=CC(C(C=CC=C5)=C5O6)=C6C=C4[N+]([O-])=O)=O)C[C@@H](O)C1)=O)C[C@@H]7N=C(C8=CC=C(Cl)C=C8)C(C(C)=C(C)S9)=C9N%10C7=NN=C%10C
Molecular Formula
C62H69ClN10O10S2
Molecular Weight
1213.86
References & Citations
[1]Weng, Weizhi et al. Development of visible-light-activatable photocaged PROTACs. European journal of medicinal chemistry, vol. 265 116062. 16 Dec. 2023
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-161093/PROTAC-BRD4-Degrader-23-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-161093/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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