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ARQ-736

ARQ-736 is a potent and selective B-RAF inhibitor that plays an important role in cancer study[1].

Product Specifications

CAS Number

[1228237-57-7]

UNSPSC

12352005

Target

Raf

Type

Reference compound

Related Pathways

MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/arq-736.html

Solubility

10 mM in DMSO

Smiles

O=P(O[Na])(O[Na])OCOC1=CC=CC(C(N=C2N3C=CO2)=C3C4=NC(N[C@H]5CN(CCC5)S(=O)(C6=NN(C)C=C6)=O)=NC=C4)=C1

Molecular Formula

C25H25N8Na2O8PS

Molecular Weight

674.53

References & Citations

[1]Tiangui Huang, et al. B-Raf and the inhibitors: from bench to bedside. J Hematol Oncol. 2013 Apr 25:6:30.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-16063/ARQ-736-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-16063/

Scientific Category

Reference compound1

Clinical Information

Phase 1

Isoform

B-Raf

Curated Selection

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