S2.2 aptamer (sodium)
Product Specifications
UNSPSC Description
S2.2 aptamer sodium is a nucleic acid aptamer targeting the mucin MUC1 and can be used for targeted imaging of MCF-7 cancer cells. S2.2 aptamer sodium was labeled with Cy5, and when fluorescent silicon nanodots (SiND) were present, the fluorescence was quenched; when MUC1 was also present, the fluorescence was restored. S2.2 aptamer sodium detects MUC1 with a linear range of 3.33-250 nM[1].
Target Antigen
Mucin
Type
Oligonucleotides
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
cancer
Assay Protocol
https://www.medchemexpress.com/s2-2-aptamer-sodium.html
Solubility
10 mM in DMSO
Smiles
[S2.2 aptamer (sodium)]
References & Citations
[1]Zhang Y, Guo S, Huang H, Mao G, Ji X, He Z. Silicon nanodot-based aptasensor for fluorescence turn-on detection of mucin 1 and targeted cancer cell imaging. Anal Chim Acta. 2018 Dec 4;1035:154-160.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-160062/S2-2-aptamer-sodium-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-160062/
Clinical Information
No Development Reported
Curated Selection
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