TNF-alpha-IN-1
TNF-alpha-IN-1 (compound 202) is an orally active inhibitor of TNF-alpha. TNF-alpha-IN-1 has anti-inflammatory activity which can used in study rheumatoid arthritis, psoriasis, and asthma[1].
Product Specifications
UNSPSC
12352005
Target
TNF Receptor
Type
Reference compound
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tnf-alpha-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H](NC([C@H](NC(CCC(NC1=CC=C(C[C@H](N2)C(N[C@@H](CC3=CC=CC=C3)C(O)=O)=O)C=C1)=O)=O)CCC4=CC=CC=C4)=O)CC5=CC=C(C6=CC=CC=C6)C=C5)C[C@H](CC7=CC=CC=C7)C2=O
Molecular Formula
C57H57N5O8
Molecular Weight
940.09
References & Citations
[1]Jinbo Lee, et al. Macrocyclic compounds for inhibition of tumor necrosis factor alpha. United States, US8338565B2. 2012-12-25.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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