J10-1

J10-1 is a hapten. J10-1 promotes peptide exchange of all DR alleles (DR1, DR2, DR4 (DRB1*0401) ) and promotes peptide binding to MHC II, which can be used in the study of immune regulation[1].

Product Specifications

CAS Number

[1069110-72-0]

UNSPSC

12352005

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/j10-1.html

Purity

99.9200

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

ClC(C=CC(NC(CC1=C(C(O)=O)NC2=C(F)C(F)=C(F)C=C12)=O)=C3)=C3Cl

Molecular Formula

C17H9Cl2F3N2O3

Molecular Weight

417.17

References & Citations

[1]Call M J. Small molecule modulators of MHC class II antigen presentation: mechanistic insights and implications for therapeutic application[J]. Molecular Immunology, 2011, 48 (15-16) : 1735-1743.