ICMT-IN-50
ICMT-IN-50 (compound 3) is an inhibitor of ICMT (IC50=0.31 μM) [1].
Product Specifications
CAS Number
[371940-21-5]
UNSPSC
12352005
Target
ICMT
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/icmt-in-50.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=CO1)CN(C2=CC=CC=C2)CCC3(CCOC(C)(C)C3)C4=CC=CC=C4
Molecular Formula
C27H31NO3
Molecular Weight
417.54
References & Citations
[1]Judd WR, et al. Discovery and SAR of methylated tetrahydropyranyl derivatives as inhibitors of isoprenylcysteine carboxyl methyltransferase (ICMT) . J Med Chem. 2011 Jul 28;54 (14) :5031-47.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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