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ICMT-IN-43

Product Specifications

UNSPSC Description

ICMT-IN-43 (compound 22) is an inhibitor of ICMT (IC50=0.04 μM)[1].

Target Antigen

ICMT

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Cancer-programmed cell death

Field of Research

cancer

Assay Protocol

https://www.medchemexpress.com/icmt-in-43.html

Solubility

10 mM in DMSO

Smiles

CCC1=CC(NCCC2(C3=CC=CC=C3)CC(C)(C)OCC2)=CC=C1

Molecular Weight

337.50

References & Citations

[1]Judd WR, et al. Discovery and SAR of methylated tetrahydropyranyl derivatives as inhibitors of isoprenylcysteine carboxyl methyltransferase (ICMT). J Med Chem. 2011 Jul 28;54(14):5031-47.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-157111/ICMT-IN-43-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-157111/

Clinical Information

No Development Reported

CAS Number

1313602-68-4

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