GLPG3667
Product Specifications
UNSPSC Description
GLPG3667 is a small molecule inhibitor of TYK2. GLPG3667 plays an important role in inflammatory diseases and/or diseases associated with hypersecretion of IFNa and/or interferons[1].
Target Antigen
JAK
Type
Reference compound
Related Pathways
Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/glpg3667.html
Solubility
10 mM in DMSO
Smiles
N#CC1=NC=C(C(C)=C1)OC2=CC(NC3=NN=C(N4CCOCC4)C=C3)=C(N=CN5C)C5=N2
Molecular Weight
443.46
References & Citations
[1]Hellot Edouard, et al. Methods of preparation of 4-methyl-5-[3-methyl-7-(6-morpholin-4-yl-pyridazin-3-ylamino)-3H-imidazo[4,5-b]pyridin-5-yloxy]-pyridine-2-carbonitrile and uses for the treatment of inflammatory diseases. World Intellectual Property Organization, WO2023161326 A1 2023-08-31
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-156961/GLPG3667-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-156961/
Clinical Information
Phase 2
CAS Number
2308520-97-8
Curated Selection
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