AChE-IN-44
AChE-IN-44 (Compound Tap4) is an AChE inhibitor. AChE-IN-44 can be converted into the thiazole salt AChE inhibitor Tat2[1].
Product Specifications
CAS Number
[2758685-58-2]
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-in-44.html
Solubility
10 mM in DMSO
Smiles
O=CN(CC1=CC=CC=C1)/C(C)=C(SSCCC(C)C)\CCNC2=C(CCCC3)C3=NC4=CC(Cl)=CC=C42
Molecular Formula
C31H38ClN3OS2
Molecular Weight
568.24
References & Citations
[1]Liu C, et al. Discovery of thiazole salt AChE inhibitors and development of thiamine disulfide prodrugs targeting the central nervous system. Bioorg Chem. 2023 Oct;139:106702.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE
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