SP4f
Product Specifications
UNSPSC Description
SP4f is an activator ofPPAR-γ, with the EC50 of 826 nM in HK-2 cells. SP4f reduces the blood glucose levels and lipid peroxidation, and increases glutathione levels and catalase activityin the Swiss albino mice[1].
Target Antigen
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/sp4f.html
Solubility
10 mM in DMSO
Smiles
O=C(N(CC1=CC=C(C)C=C1)C/2=O)SC2=C/C3=CC=C(NC4=CC=CC(Cl)=C4)S3
Molecular Weight
440.97
References & Citations
[1]Gupta S, et al. Integrated fragment-based drug design and virtual screening techniques for exploring the antidiabetic potential of thiazolidine-2,4-diones: Design, synthesis and in vivo studies [published online ahead of print, 2023 Sep 21]. Eur J Med Chem. 2023;261:115826.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-156277/SP4f-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-156277/
Clinical Information
No Development Reported
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