Antifungal agent 71

Antifungal agent 71 (compound 6r) is a trifluoromethyl pyrimidine derivative with antifungal activity. Antifungal agent 71 exhibits good in vitro antifungal activity against F. oxysporum, with the EC50 value of 3.61 μg/mL[1].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352005

Target

Fungal

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antifungal-agent-71.html

Solubility

10 mM in DMSO

Smiles

FC(C1=NC(C)=NC(NCC2=CC=C(C3=NN=C(SCC4=C(F)C=CC=C4F)O3)C=C2)=C1)(F)F

Molecular Formula

C22H16F5N5OS

Molecular Weight

493.45

References & Citations

[1]Nianjian Pan, et al. Design, synthesis, antifungal activity, and molecular docking of novel trifluoromethyl pyrimidine derivatives containing 1,3,4‐oxadiazole and thioether moieties as potential succinate dehydrogenase inhibitors. Journal of Heterocyclic Chemistry. 1 August 2023.