Antimalarial agent 28
Antimalarial agent 28 (Compound 2i) is an antiplasmodial agent. Antimalarial agent 28 inhibits P. berghei, with IC50s of 0.561 μM, 0.14 μM, 4.34 μM for Liver stage, early gametocytes and ring stages of P. falciparum[1].
Product Specifications
CAS Number
[9007-83-4]
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antimalarial-agent-28.html
Solubility
10 mM in DMSO
Smiles
O=C(NCCCCNC1=CC(OC)=CC2=CC3=CC=C(Cl)C=C3N=C12)/C=C/C4=CC=CC(F)=C4
Molecular Formula
C27H25ClFN3O2
Molecular Weight
477.96
References & Citations
[1]Fonte M, et al. New 4- (N-cinnamoylbutyl) aminoacridines as potential multi-stage antiplasmodial leads. Eur J Med Chem. 2023 Oct 5;258:115575.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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