PROTAC BRD9 Degrader-7
Product Specifications
UNSPSC Description
PROTAC BRD9 Degrader-7 is an orally active and selective degrader of BRD9 with a DC50 of 1.02 nM. PROTAC BRD9 Degrader-7 has superior oral activity with a Cmax of 3436.95 ng/mL[1].
Target Antigen
PROTACs
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-brd9-degrader-7.html
Purity
99.29
Solubility
DMSO : 70 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=C(N(C)C=C1C2=CC(OC)=C(CN3CCN(C4=CC=C5C(C(N(C6C(NC(CC6)=O)=O)C5=O)=O)=C4)CC3)C(OC)=C2)C7=C1C=CC=C7
Molecular Weight
649.69
References & Citations
[1]Jingyu Zhang, et al. Structure-based identification of new orally bioavailable BRD9-PROTACs for treating acute myelocytic leukemia, European Journal of Medicinal Chemistry, Volume 262, 2023, 115872.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-155361/PROTAC-BRD9-Degrader-7-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-155361/PROTAC-BRD9-Degrader-7-SDS-MedChemExpress.pdf
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Clinical Information
No Development Reported
Curated Selection
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