VEGFR-2-IN-35
VEGFR-2-IN-35 (compound 7) is a potent VEGFR-2 inhibitor with IC50=37 nM. VEGFR-2-IN-35 inhibits MCF-7 and HCT 116 cancer cells with IC50 values of 10.56 and 7.07 μM, respectively[1].
Product Specifications
CAS Number
[2634356-52-6]
UNSPSC
12352005
Target
VEGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vegfr-2-in-35.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C(NC(C2=CC=CC=C2)=O)C=C1)N/N=C/C3=CC(C=CC=C4)=C4C=C3O
Molecular Formula
C25H19N3O3
Molecular Weight
409.44
References & Citations
[1]Elkaeed EB, et al. In silico, in vitro VEGFR-2 inhibition, and anticancer activity of a 3- (hydrazonomethyl) naphthalene-2-ol derivative. J Biomol Struct Dyn. 2023 Sep-Oct;41 (16) :7986-8001.. .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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