N6-Bz-5’-O-DMTr-2’-O-hexadecanyl adenosine 3’-CED phosphoramidite
Product Specifications
UNSPSC Description
N6-Bz-5’-O-DMTr-2’-O-hexadecanyl adenosine 3’-CED phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Target Antigen
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n6-bz-5-o-dmtr-2-o-hexadecanyl-adenosine-3-ced-phosphoramidite.html
Solubility
10 mM in DMSO
Smiles
CC(C)N(C(C)C)P(O[C@H]1[C@H]([C@H](N(C=N2)C3=C2C(NC(C4=CC=CC=C4)=O)=NC=N3)O[C@@H]1COC(C5=CC=CC=C5)(C6=CC=C(OC)C=C6)C7=CC=C(OC)C=C7)OCCCCCCCCCCCCCCCC)OCCC#N
Molecular Weight
1098.36
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-154623/N6-Bz-5-O-DMTr-2-O-hexadecanyl-adenosine-3-CED-phosphoramidite-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-154623/
Clinical Information
No Development Reported
CAS Number
2382942-35-8
Curated Selection
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