2′-Deoxy-6-thioinosine
2′-Deoxy-6-thioinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
[2239-64-7]
UNSPSC
12352005
Hazard Statement
H302
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-deoxy-6-thioinosine.html
Solubility
10 mM in DMSO
Smiles
OC[C@@H]1[C@@H](O)C[C@H](N2C=NC3=C2N=CNC3=S)O1
Molecular Formula
C10H12N4O3S
Molecular Weight
268.29
Precautions
P264-P270-P330-P501
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
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