1-Isopropyltryptophan
1-Isopropyltryptophan (1-IsoPT) is a IDO1 inhibitor. 1-Isopropyltryptophan decreases the expression of IFN-γ stimulated ID0-1 and ID0-2 mRNA[1].
Product Specifications
CAS Number
[1219485-46-7]
Product Name Alternative
1-IsoPT
UNSPSC
12352005
Target
Indoleamine 2,3-Dioxygenase (IDO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/1-isopropyltryptophan.html
Solubility
10 mM in DMSO
Smiles
N[C@@H](CC1=CN(C(C)C)C2=C1C=CC=C2)C(O)=O
Molecular Formula
C14H18N2O2
Molecular Weight
246.30
References & Citations
[1]Sun T, et al. Novel 1-alkyl-tryptophan derivatives downregulate IDO1 and IDO2 mRNA expression induced by interferon-gamma in dendritic cells. Mol Cell Biochem. 2010 Sep;342 (1-2) :29-34.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IDO1
Curated Selection
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