(R) -Capivasertib
(R) -Capivasertib ((R) -AZD5363) is the R-enantiomer of Capivasertib (HY-15431) [1].
Product Specifications
CAS Number
[1143532-51-7]
Product Name Alternative
(R) -AZD5363
UNSPSC
12352005
Target
Akt
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/r-capivasertib.html
Purity
99.56
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1(N)CCN(C2=C3C(NC=C3)=NC=N2)CC1)N[C@@H](C4=CC=C(Cl)C=C4)CCO
Molecular Formula
C21H25ClN6O2
Molecular Weight
428.92
References & Citations
[1]Davies BR, et al. Preclinical pharmacology of AZD5363, an inhibitor of AKT: pharmacodynamics, antitumor activity, and correlation of monotherapy activity with genetic background. Mol Cancer Ther. 2012 Apr;11 (4) :873-87.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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