Rev 2’-O-MOE-G(iBu)-5’-amidite
Product Specifications
UNSPSC Description
Rev 2’-O-MOE-G(iBu)-5’-amidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Target Antigen
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rev-2-o-moe-g-ibu-5-amidite.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(N([C@H]3[C@H](OCCOC)[C@H](OC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)[C@@H](COP(N(C(C)C)C(C)C)OCCC#N)O3)C=N2)N=C(NC(C(C)C)=O)N1
Molecular Weight
913.99
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-154259/Rev-2-O-MOE-G-iBu-5-amidite-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-154259/
Clinical Information
No Development Reported
CAS Number
725223-44-9
Curated Selection
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