4-Deoxy-3’-deoxy-3’-fluoro uridine
4-Deoxy-3’-deoxy-3’-fluoro uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/4-deoxy-3-deoxy-3-fluoro-uridine.html
Solubility
10 mM in DMSO
Smiles
O=C1N=CC=CN1[C@H]2[C@H](O)[C@H](F)[C@@H](CO)O2
Molecular Formula
C9H11FN2O4
Molecular Weight
230.19
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-154203/4-Deoxy-3-deoxy-3-fluoro-uridine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-154203/
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
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