BTK-IN-26
BTK-IN-26 (compound 18) is a potent inhibitor of Bruton's tyrosine kinase (BTK) and its C481 mutant, with IC50 values of 0.7 and 0.8 nM for BTK and BTK C481S, respectively. BTK-IN-26 can be used for cancer and autoimmune diseases research[1].
Product Specifications
CAS Number
[2762043-61-6]
UNSPSC
12352005
Target
Btk
Type
Isotope-Labeled Compounds
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Solubility
10 mM in DMSO
Smiles
NC1=NC=NN2C([C@@H]3CC[C@H](CC3)CO)=NC(C4=CC=C(C=C4)CNC(C5=C(C=CC(F)=C5)OC([2H])([2H])[2H])=O)=C12
Molecular Formula
C27H26D3FN6O3
Molecular Weight
507.57
References & Citations
[1]Xiangyang Chen, et al. Heterocyclic compounds as btk inhibitors. Patent, WO2022037649A1.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Curated Selection
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