C-Met-IN-17
C-Met-IN-17 is a potent c-Met kinase inhibitor with an IC50 of 0.031 μM. c-Met-IN-17 can be used in anticancer research.[1]. c-Met-IN-17 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
CAS Number
[3034863-55-0]
UNSPSC
12352005
Target
C-Met/HGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/c-met-in-17.html
Solubility
10 mM in DMSO
Smiles
FC1=CC2=C(C(C3=CN(C(NC3=O)=O)C(C4=CC=CC=C4)C)=C1)NN=C2C#C
Molecular Formula
C21H15FN4O2
Molecular Weight
374.37
References & Citations
[1]Michaelides IN, et al. Discovery and Optimization of the First ATP Competitive Type-III c-MET Inhibitor. J Med Chem. 2023 Jul 13;66 (13) :8782-8807.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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