AST 7062601
Product Specifications
UNSPSC Description
AST 7062601 (AST070) is a Ucp1 inducer that strongly induces endogenous Ucp1 expression in primary mouse brown adipocytes. Ucp1 refers to uncoupling protein, found in brown and beige fat cells. In mammals, UCP1 oxidizes fatty acids and uncouples ATP production in mitochondria to promote energy dissipation as heat. AST 7062601 can be used to study thermogenic, uncoupled respiration[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ast-7062601.html
Solubility
10 mM in DMSO
Smiles
O=C1N=C(NC2=C1C=CC=C2)SCC(NC3=CC=C4OCCOC4=C3)=O
Molecular Weight
369.39
References & Citations
[1]Vergnes L, et al. Induction of UCP1 and thermogenesis by a small molecule via AKAP1/PKA modulation. J Biol Chem. 2020 Oct 30;295(44):15054-15069.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-153812/AST-7062601-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-153812/
Clinical Information
No Development Reported
CAS Number
675197-89-4
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS2089738-01 5x 96 Tests
Human Vascular Endothelial Growth Factor D (VEGFD) Antibody Pair Kit (with Standard)
Ask
View Details MBS2089738-02 5x 96 Tests + MBS2090685 (Ab Pairs Support Pack 1,5x 96 Tests)
Human Vascular Endothelial Growth Factor D (VEGFD) Antibody Pair Kit (with Standard)
Ask
View Details 
MBS2089738-03 10x 96 Tests
Human Vascular Endothelial Growth Factor D (VEGFD) Antibody Pair Kit (with Standard)
Ask
View Details MBS2089738-04 10x 96 Tests + MBS2090685 (Ab Pairs Support Pack 1, 10x 96 Tests)
Human Vascular Endothelial Growth Factor D (VEGFD) Antibody Pair Kit (with Standard)
Ask
View Details