AP-C2
Product Specifications
UNSPSC Description
AP-C2 is a potent guanosine 3',5'-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) inhibitor with a pIC50 of 5.2[1].
Target Antigen
Ser/Thr Protease
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ap-c2.html
Solubility
10 mM in DMSO
Smiles
C1(C2=CC=CS2)=CC=NC(NCCC3=CNC4=C3C=CC=C4)=N1
Molecular Weight
320.41
References & Citations
[1]Marcel J C Bijvelds, et al. Selective inhibition of intestinal guanosine 3',5'-cyclic monophosphate signaling by small-molecule protein kinase inhibitors. J Biol Chem. 2018 May 25;293(21):8173-8181.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-153538/AP-C2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-153538/
Clinical Information
No Development Reported
CAS Number
682793-07-3
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