KRASG12C IN-2
Product Specifications
UNSPSC Description
KRASG12C IN-2 (compound 17) is an orally active KRASG12C inhibitor. KRASG12C IN-2 inhibits tumor growth in mice[1].
Target Antigen
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein;MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/krasg12c-in-2.html
Solubility
10 mM in DMSO
Smiles
FC(F)(F)C(C(C)=CC(N)=C1F)=C1[C@H]2CC3=NC(OC[C@@]45N(CCC5)C[C@@H](C4)F)=NC(N6C[C@@H](N(CC6)C(C(F)=C)=O)CC#N)=C3CO2
Molecular Weight
679.66
References & Citations
[1]Zhang Yang, et al. Pyrimidoheterocyclic compounds and application thereof. WO2021180181A1.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-153262/KRASG12C-IN-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-153262/
Clinical Information
No Development Reported
CAS Number
2706637-12-7
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